HLA-DRB1*15:01 and the MERTK Gene Interact to Selectively Influence the Profile of MERTK-Expressing Monocytes in Both Health and MS
- Creator: Binder, Michele D. , Nwoke, Eze C. , Kilpatrick, Trevor J. , Ausimmune Investigator Group, , Morwitch, Ellen , Dwyer, Chris , Li, Vivien , Xavier, Alexandre , Lea, Rodney A. , Lechner-Scott, Jeannette , Taylor, Bruce V. , Ponsonby, Anne-Louise
- Resource Type: journal article
- Date: 2024
A pro-inflammatory diet in people with multiple sclerosis is associated with an increased rate of relapse and increased FLAIR lesion volume on MRI in early multiple sclerosis: A prospective cohort study
- Creator: Saul, Alice M. , Taylor, Bruce V. , Lechner-Scott, Jeanette , van der Mei, Ingrid , Blizzard, Leigh , Simpson-Yap, Steve , Oddy, Wendy H. , Shivappa, Nittin , Hébert, James R. , Black, Lucinda J. , Ponsonby, Anne-Louise , Broadley, Simon A.
- Resource Type: journal article
- Date: 2023
DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes
- Creator: Xavier, Alexandre , Maltby, Vicki E. , Jokubaitis, Vilija G. , Kilpatrick, Trevor , Alfredsson, Lars , Jagodic, Maja , Ponsonby, Anne-Louise , Taylor, Bruce V. , Scott, Rodney J. , Lea, Rodney A. , Lechner-Scott, Jeannette , Ewing, Ewoud , Campagna, Maria Pia , Burnard, Sean M. , Tegner, Jesper N. , Slee, Mark , Butzkueven, Helmut , Kockum, Ingrid , Kular, Lara
- Resource Type: journal article
- Date: 2023
Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis
- Creator: Maltby, Vicki , Xavier, Alexandre , Slee, Mark , van der Mei, Ingrid A. , Taylor, Bruce V. , Ponsonby, Anne-Louise , Jagodic, Maja , Lea, Rodney , Lechner-Scott, Jeannette , Ewing, Ewoud , Campagna, Maria-Pia , Sampangi, Sandeep , Scott, Rodney J. , Butzkueven, Helmut , Jokubaitis, Vilija , Kular, Lara , Bos, Steffan
- Resource Type: journal article
- Date: 2023
Interferon beta treatment is a potent and targeted epigenetic modifier in multiple sclerosis
- Creator: Xavier, Alexandre , Campagna, Maria Pia , Lechner-Scott, Jeannette , Ausimmune Investigator Group, , Maltby, Vicki E. , Kilpatrick, Trevor , Taylor, Bruce V. , Butzkueven, Helmut , Ponsonby, Anne-Louise , Scott, Rodney J. , Jokubaitis, Vilija G. , Lea, Rodney A.
- Resource Type: journal article
- Date: 2023
Not all roads lead to the immune system: the genetic basis of multiple sclerosis severity
- Creator: Jokubaitis, Vilija G. , Campagna, Maria Pia , Lea, Rodney , Kilpatrick, Trevor J. , Kalincik, Tomas , De Jager, Philip L. , Beecham, Ashley , McCauley, Jacob L. , Taylor, Bruce V. , Vucic, Steve , Laverick, Louise , Vodehnalova, Karolina , Ibrahim, Omar , García-Sanchéz, Maria-Isabel , Alcina, A , van der Walt, A , Havrdova, EK , Izquierdo, G , Patsopoulos, N , Horakova, D , Butzkueven, H , Stankovich, Jim , Kleinova, Pavlina , Matesanz, Fuencisla , Hui, Daniel , Eichau, Sara , Slee, Mark , Lechner-Scott, Jeannette
- Resource Type: journal article
- Date: 2023
The association between disability progression, relapses, and treatment in early relapse onset MS: an observational, multi-centre, longitudinal cohort study.
- Creator: Fuh-Ngwa, Valery , Charlesworth, Jac C. , Zhou, Yuan , van der Mei, Ingrid , Melton, Phillip E. , Broadley, Simon A. , Ponsonby, Anne-Louise , Simpson-Yap, Steve , Lechner-Scott, Jeannette , Taylor, Bruce V.
- Resource Type: journal article
- Date: 2023
Ensemble machine learning identifies genetic loci associated with future worsening of disability in people with multiple sclerosis
- Creator: Fuh-Ngwa, Valery , Zhou, Yuan , Melton, Phillip E. , van der Mei, Ingrid , Charlesworth, Jac C. , Lin, Xin , Zarghami, Amin , Broadley, Simon A. , Ponsonby, Anne-Louise , Simpson-Yap, Steve , Lechner-Scott, Jeannette , Taylor, Bruce V.
- Resource Type: journal article
- Date: 2022
Long-term trajectories of employment status, workhours and disability support pension status, after a first episode of CNS demyelination
- Creator: Zarghami, Amin , van der Mei, Ingrid , Taylor, Bruce V. , AusLong Investigator Group, , Hussain, Mohammad Akhtar , Claflin, Suzi B. , Bessing, Barnabas , Simpson-Yap, Steve , Ponsonby, Anne-Louise , Lechner-Scott, Jeanette , Broadley, Simon , Blizzard, Leigh
- Resource Type: journal article
- Date: 2022
Developing a clinical-environmental-genotypic prognostic index for relapsing-onset multiple sclerosis and clinically isolated syndrome
- Creator: Fuh-Ngwa, Valery , Zhou, Yuan , Charlesworth, Jac C. , Ponsonby, Anne-Louise , Simpson-Yap, Steve , Lechner-Scott, Jeanette , Taylor, Bruce V.
- Resource Type: journal article
- Date: 2021
Estimation of annual probabilities of changing disability levels in Australians with relapsing-remitting multiple sclerosis
- Creator: Ahmad, Hasnat , van der Mei, Ingrid , Palmer, Andrew J. , Taylor, Bruce V. , Lucas, Robyn M. , Ponsonby, Anne-Louise , Lechner-Scott, Jeannette , Dear, Keith , Valery, Patricia , Clarke, Philip M. , Simpson, Steve
- Resource Type: journal article
- Date: 2019
Common genetic variation within miR-146a predicts disease onset and relapse in multiple sclerosis
- Creator: Zhou, Yuan , Chen, Ming , Dear, Keith , Dwyer, Terry , Blizzard, Leigh , Simpson, Steve , Taylor, Bruce V. , Broadley, Simon , Kilpatrick, Trevor , Williams, David , Lechner-Scott, Jeanette , Shaw, Cameron , Chapman, Caron , Coulthard, Alan , Valery, Patricia , Valery, P , Taylor, BV , Lucas, Robyn M. , Charlesworth, Jac C. , Blackburn, Nicholas , van der Mei, Ingrid , Ponsonby, Anne-Louise
- Resource Type: journal article
- Date: 2018
Onset symptoms, Tobacco smoking, and progressive-onset phenotype are associated with a delayed onset of multiple sclerosis, and marijuana use with an earlier onset
- Creator: Tao, Chunrong , Simpson, Steve , Kilpatrick, Trevor , Williams, David , Lechner-Scott, Jeanette , Shaw, Cameron , Chapman, Caron , Coulthard, Alan , Pender, Michael P. , Valery, Patricia , Taylor, Bruce V. , Blizzard, Leigh , Lucas, Robyn M. , Ponsonby, Anne-Louise , Broadley, Simon , van der Mei, Ingrid , Dear, Keith , Dwyer, Terry
- Resource Type: journal article
- Date: 2018
Variation within MBP gene predicts disease course in multiple sclerosis
- Creator: Zhou, Yuan , Simpson Jr, Steve , Taylor, Bruce V. , Charlesworth, Jac C. , van der Mei, Ingrid , Lucas, Robyn M. , Ponsonby, Anne-Louise , Taylor, Anne-Louise , AUSLONG Investigators Group, , Williams, David , Lechner-Scott, Jeanette
- Resource Type: journal article
- Date: 2017
Higher latitude is significantly associated with an earlier age of disease onset in multiple sclerosis
- Creator: Tao, Chunrong , Simpson, Steve , Duquette, Pierre , Girard, Marc , Grand'Maison, Francois , Grammond, Pierre , Alroughani, Raed , Terzi, Murat , Oreja-Guevara, Celia , Sajedi, Seyed Aidin , Iuliano, Gerardo , Sola, Patrizia , van der Mei, Ingrid , Lechner-Scott, Jeannette , Van Pesch, Vincent , Pucci, Eugenio , Bergamaschi, Roberto , Barnett, Michael , Ramo, Cristina , Singhal, Bhim , Spitaleri, Daniele L. A. , Slee, Mark , Verheul, Freek , Blizzard, Leigh , Fernández Bolaños, Ricardo , Amato, Maria Pia , Cristiano, Edgardo , Granella, Franco , Hodgkinson, Suzanne , Fiol, Marcela , Gray, Orla , McCombe, Pamela , Saladino, Maria Laura , Sánchez Menoyo, José Luis , Havrdova, Eva , Shuey, Neil , Vucic, Steve , Shaw, Cameron , Deri, Norma , Arruda, Walter Oleschko , Butzkueven, Helmut , Spelman, Tim , Taylor, Bruce V. , Horakova, Dana , Shaygannejad, Vahid , Lugaresi, Alessandra , Izquierdo, Guillermo , Trojano, Maria
- Resource Type: journal article
- Date: 2016
Role of genetic susceptibility variants in predicting clinical course in multiple sclerosis: a cohort study
- Creator: Pan, Gongbu , Simpson, Steve , Williams, David , Lechner-Scott, Jeannette , Van Der Mei, Ingrid , Charlesworth, Jac C. , Lucas, Robyn , Ponsonby, Anne-Louise , Zhou, Yuan , Taylor, Bruce V.
- Resource Type: journal article
- Date: 2016
A new era in the treatment of multiple sclerosis
- Creator: Broadley, Simon A. , Barnett, Michael H. , Marriott, Mark , Mason, Deborah F. , Parratt, John , Reddel, Stephen W. , Shaw, Cameron P. , Slee, Mark , Spies, Judith M. , Taylor, Bruce V. , Carroll, William M. , Kilpatrick, Trevor J. , Boggild, Mike , King, John , McCombe, Pamela A. , Pollard, John D. , Willoughby, Ernest , Brew, Bruce J. , Butzkueven, Helmut , Heard, Robert , Hodgkinson, Suzanne , Kermode, Allan G. , Lechner-Scott, Jeannette , Macdonell, Richard A. L.
- Resource Type: journal article
- Date: 2015
A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis
- Creator: Gu, Ben J. , Field, Judith , Butzkueven, Helmut , Gresle, Melissa , Laws, Simon M. , Petrou, Steven , Hoffjan, Sabine , Akkad, Denis A. , Graham, Colin A. , Hawkins, Stanley , Glaser, Anna , Bedri, Sahl Khalid , Dutertre, Sébastien , Hillert, Jan , Matute, Carlos , Antiguedad, Alfredo , Wiley, James S. , Ou, Amber , Kilpatrick, Trevor J. , Lechner-Scott, Jeannette , Scott, Rodney , Lea, Rodney , Taylor, Bruce V. , Stankovich, Jim
- Resource Type: journal article
- Date: 2015
Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 1 Historical and established therapies
- Creator: Broadley, Simon A. , Barnett, Michael H. , Marriott, Mark , Mason, Deborah F. , Parratt, John , Reddel, Stephen W. , Shaw, Cameron P. , Slee, Mark , Spies, Judith , Taylor, Bruce V. , Carroll, William M. , Kilpatrick, Trevor J. , Boggild, Mike , King, John , McCombe, Pamela A. , Pollard, John D. , Willoughby, Ernest , Brew, Bruce J. , Butzkueven, Helmut , Heard, Robert , Hodgkinson, Suzanne , Kermode, Allan G. , Lechner-Scott, Jeannette , Macdonell, Richard A. L.
- Resource Type: journal article
- Date: 2014
Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: An Australian and New Zealand perspective Part 2 New and emerging therapies and their efficacy
- Creator: Broadley, Simon A. , Barnett, Michael H. , Marriott, Mark , Mason, Deborah F. , Parratt, John , Reddel, Stephen W. , Shaw, Cameron P. , Slee, Mark , Spies, Judith , Taylor, Bruce V. , Carroll, William M. , Kilpatrick, Trevor J. , Boggild, Mike , King, John , McCombe, Pamela A. , Pollard, John D. , Willoughby, Ernest , Brew, Bruce J. , Butzkueven, Helmut , Heard, Robert , Hodgkinson, Suzanne , Kermode, Allan G. , Lechner-Scott, Jeannette , Macdonell, Richard A. L.
- Resource Type: journal article
- Date: 2014